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                key:"content": string:"Korištenjem genske terapije, znanstvenici su otkrili da je upravljanje razinom proteina GDNF ključno za ispravnu transmisiju dopamina, neurotransmitera koji izaziva osjećaj ugode, u mozgu. Razine GDNF naglo opadaju kada alkoholičari prestanu piti, što dovodi do nedostatka dopamina i osjećaja nelagode, što prisiljava alkoholičare da se vrate pijenju. Sada se smatra da genska terapija može 'popraviti' razine GDNF, što bi moglo biti rješenje za one koji pate od alkoholizma.",
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                key:"title": string:"Ceea ce este corect: cercetătorii ar putea fi pe punctul de a descoperi un tratament revoluționar pentru alcoolism.",
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                key:"content": string:"Folosind terapia genică, oamenii de știință au descoperit că gestionarea nivelului proteinei GDNF este cheia pentru transmiterea corectă a dopaminei, neurotransmițătorul care induce o stare de bine, în creier. Nivelurile de GDNF scad brusc atunci când alcoolicii se abțin de la băut, ceea ce duce la o lipsă de dopamină și la o senzație de disconfort, ceea ce îi face pe alcoolici să recurgă la băut. Terapia genică este acum considerată a 'repara' nivelurile de GDNF, ceea ce ar putea fi o soluție pentru cei care suferă de alcoolism.",
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                key:"summary": string:"Folosind terapia genică, oamenii de știință au descoperit că gestionarea nivelului proteinei GDNF este cheia pentru transmiterea corectă a dopaminei, neurotransmițătorul care induce o stare de bine, în creier. Nivelurile de GDNF scad brusc atunci când alcoolicii se abțin de la băut, ceea ce duce la o lipsă de dopamină și la o senzație de disconfort, ceea ce îi face pe alcoolici să recurgă la băut. Terapia genică este acum considerată a 'repara' nivelurile de GDNF, ceea ce ar putea fi o soluție pentru cei care suferă de alcoolism.",
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                key:"title": string:"Изследователите може да са на ръба на революционно лечение за алкохолизъм.",
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                key:"content": string:"Чрез генна терапия учените откриха, че управлението на нивото на протеина GDNF е ключово за правилната предаване на допамина, невротрансмитера, който предизвиква добро настроение, в мозъка. Нивата на GDNF рязко спадат, когато алкохолиците се въздържат от пиене, което води до недостиг на допамин и чувство на дискомфорт, което кара алкохолиците да се върнат към пиенето. Сега се смята, че генната терапия може да \"поправи\" нивата на GDNF, което би могло да бъде решение за тези, които страдат от алкохолизъм.",
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                key:"summary": string:"Чрез генна терапия учените откриха, че управлението на нивото на протеина GDNF е ключово за правилната предаване на допамина, невротрансмитера, който предизвиква добро настроение, в мозъка. Нивата на GDNF рязко спадат, когато алкохолиците се въздържат от пиене, което води до недостиг на допамин и чувство на дискомфорт, което кара алкохолиците да се връщат към пиенето. Сега се смята, че генната терапия може да \"поправи\" нивата на GDNF, което би могло да бъде решение за тези, които страдат от алкохолизъм.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"bg",
                key:"updatedAt": string:"2025-02-10T12:59:04.847",
                key:"__typename": string:"ContentItemTranslation"
            },
            {
                key:"title": string:"Researchers may be on the brink of a ground-breaking cure for alcoholism.",
                key:"uid": string:"43be5ced-0399-4129-9325-9ea469a33c62",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Using gene therapy, scientists have discovered that managing the level of the protein GDNF is key to the correct transmission of dopamine, the feel-good neurotransmitter, in the brain. GDNF levels plummet when alcoholics abstain from drinking, leading to a dopamine shortage and feeling of discomfort, which makes alcoholics resort to drinking. Gene therapy is now thought to 'fix' GDNF levels, which could be a solution for those suffering from alcoholism.",
                key:"contentCleaned": null:null,
                key:"contentItemUid": string:"eaynwovfmq5sqrcq4g7xd5v43qy",
                key:"createdAt": string:"2025-02-10T13:15:21.873",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vaynwovgknwzqrib2njfxfz4hac",
                key:"subtitle": null:null,
                key:"summary": string:"Using gene therapy, scientists have discovered that managing the level of the protein GDNF is key to the the correct transmission of dopamine, the feel-good neurotransmitter, in the brain. GDNF levels plummet when alcoholics abstain from drinking, leading to a dopamine shortage and feeling of discomfort, which makes alcoholics resort to drinking. Gene therapy is now thought to 'fix' GDNF levels, which could be a solution for those suffering from alcoholism.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"en",
                key:"updatedAt": string:"2025-02-10T13:15:52.347",
                key:"__typename": string:"ContentItemTranslation"
            },
            {
                key:"title": string:"Дослідники можуть бути на межі революційного лікування алкоголізму.",
                key:"uid": string:"4a9a6e19-4b08-46c3-aa4e-c2a6cfdf8220",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": null:null,
                key:"contentCleaned": null:null,
                key:"contentItemUid": string:"eaynwovfmq5sqrcq4g7xd5v43qy",
                key:"createdAt": string:"2025-02-12T11:55:11.706",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vaynwovgknwzqrib2njfxfz4hac",
                key:"subtitle": null:null,
                key:"summary": null:null,
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"uk",
                key:"updatedAt": null:null,
                key:"__typename": string:"ContentItemTranslation"
            },
            {
                key:"title": string:"Araştırmacılar alkolizm için çığır açan bir tedaviye çok yakın olabilir.",
                key:"uid": string:"517abd22-2fc5-4e58-9a85-e576fdfa42be",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Gen tedavisi kullanarak, bilim insanları GDNF protein seviyesinin, beynin iyi hissettiren nörotransmitteri dopaminin doğru iletimi için anahtar olduğunu keşfettiler. Alkolikler içki içmeyi bıraktıklarında GDNF seviyeleri düşer, bu da dopamin eksikliğine ve rahatsızlık hissine yol açar; bu da alkoliklerin içki içmeye yönelmesine neden olur. Gen tedavisinin şimdi GDNF seviyelerini 'düzeltmesi' gerektiği düşünülüyor; bu da alkolizmden muzdarip olanlar için bir çözüm olabilir.",
                key:"contentCleaned": null:null,
                key:"contentItemUid": string:"eaynwovfmq5sqrcq4g7xd5v43qy",
                key:"createdAt": string:"2025-02-10T12:52:38.459",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vaynwovgknwzqrib2njfxfz4hac",
                key:"subtitle": null:null,
                key:"summary": string:"Gen tedavisi kullanarak, bilim insanları GDNF protein seviyesinin, beynin iyi hissettiren nörotransmitteri dopaminin doğru iletimi için anahtar olduğunu keşfettiler. Alkolikler içki içmeyi bıraktıklarında GDNF seviyeleri düşer, bu da dopamin eksikliğine ve rahatsızlık hissine yol açar; bu da alkoliklerin içki içmeye yönelmesine neden olur. Gen tedavisinin şimdi GDNF seviyelerini 'düzeltmesi' gerektiği düşünülüyor, bu da alkolizmden muzdarip olanlar için bir çözüm olabilir.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"tr",
                key:"updatedAt": string:"2025-02-10T12:52:38.46",
                key:"__typename": string:"ContentItemTranslation"
            },
            {
                key:"title": string:"Badania mogą być na progu przełomowego lekarstwa na alkoholizm.",
                key:"uid": string:"55b422b4-f716-4d7e-ac17-b6202d4076a9",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Za pomocą terapii genowej naukowcy odkryli, że zarządzanie poziomem białka GDNF jest kluczowe dla prawidłowego przekazywania dopaminy, neuroprzekaźnika odpowiedzialnego za dobre samopoczucie, w mózgu. Poziomy GDNF spadają, gdy alkoholicy powstrzymują się od picia, co prowadzi do niedoboru dopaminy i uczucia dyskomfortu, co sprawia, że alkoholicy sięgają po alkohol. Terapię genową uważa się teraz za sposób na 'naprawienie' poziomów GDNF, co mogłoby być rozwiązaniem dla osób cierpiących na alkoholizm.",
                key:"contentCleaned": null:null,
                key:"contentItemUid": string:"eaynwovfmq5sqrcq4g7xd5v43qy",
                key:"createdAt": string:"2025-02-10T13:09:04.813",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vaynwovgknwzqrib2njfxfz4hac",
                key:"subtitle": null:null,
                key:"summary": string:"Za pomocą terapii genowej naukowcy odkryli, że zarządzanie poziomem białka GDNF jest kluczowe dla prawidłowego przekazywania dopaminy, neuroprzekaźnika odpowiedzialnego za dobre samopoczucie, w mózgu. Poziomy GDNF spadają, gdy alkoholicy powstrzymują się od picia, co prowadzi do niedoboru dopaminy i uczucia dyskomfortu, co sprawia, że alkoholicy sięgają po alkohol. Terapię genową uważa się teraz za sposób na 'naprawienie' poziomów GDNF, co mogłoby być rozwiązaniem dla osób cierpiących na alkoholizm.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"pl",
                key:"updatedAt": string:"2025-02-10T13:09:24.52",
                key:"__typename": string:"ContentItemTranslation"
            },
            {
                key:"title": string:"A kutatók a szenvedélybetegségek forradalmi gyógymódjának küszöbén állhatnak.",
                key:"uid": string:"5a32c382-132d-453d-80ce-870e29ed1498",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"A génterápia segítségével a tudósok felfedezték, hogy a GDNF fehérje szintjének kezelése kulcsfontosságú a dopamin, a jó közérzet neurotranszmitterének helyes átviteléhez az agyban. A GDNF szintje drámaian csökken, amikor az alkoholisták tartózkodnak az ivástól, ami dopaminhiányhoz és kényelmetlen érzéshez vezet, ami miatt az alkoholisták újra inni kezdenek. A génterápia most úgy tűnik, hogy \"javítja\" a GDNF szintjét, ami megoldást jelenthet az alkoholizmusban szenvedők számára.",
                key:"contentCleaned": null:null,
                key:"contentItemUid": string:"eaynwovfmq5sqrcq4g7xd5v43qy",
                key:"createdAt": string:"2025-02-10T12:30:53.715",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vaynwovgknwzqrib2njfxfz4hac",
                key:"subtitle": null:null,
                key:"summary": string:"A génterápia segítségével a tudósok felfedezték, hogy a GDNF fehérje szintjének kezelése kulcsfontosságú a dopamin, a jó közérzet neurotranszmitterének helyes átviteléhez az agyban. A GDNF szintje drámaian csökken, amikor az alkoholisták tartózkodnak az ivástól, ami dopaminhiányhoz és kényelmetlenséghez vezet, ami miatt az alkoholisták újra inni kezdenek. A génterápia most úgy tűnik, hogy \"javítja\" a GDNF szintet, ami megoldást jelenthet az alkoholizmusban szenvedők számára.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"hu",
                key:"updatedAt": string:"2025-02-10T12:30:53.716",
                key:"__typename": string:"ContentItemTranslation"
            },
            {
                key:"title": string:"Onderzoekers staan mogelijk op de rand van een baanbrekende genezing voor alcoholisme.",
                key:"uid": string:"69abb255-0bb2-4480-a8da-25b7f2da98c8",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Met behulp van gentherapie hebben wetenschappers ontdekt dat het beheersen van het niveau van het eiwit GDNF essentieel is voor de juiste overdracht van dopamine, de feel-good neurotransmitter, in de hersenen. GDNF-niveaus dalen drastisch wanneer alcoholisten zich onthouden van drinken, wat leidt tot een tekort aan dopamine en een gevoel van ongemak, waardoor alcoholisten weer naar alcohol grijpen. Gentherapie wordt nu beschouwd als een manier om de GDNF-niveaus te 'repareren', wat een oplossing zou kunnen zijn voor degenen die lijden aan alcoholisme.",
                key:"contentCleaned": null:null,
                key:"contentItemUid": string:"eaynwovfmq5sqrcq4g7xd5v43qy",
                key:"createdAt": string:"2025-02-10T12:52:31.681",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vaynwovgknwzqrib2njfxfz4hac",
                key:"subtitle": null:null,
                key:"summary": string:"Door middel van gentherapie hebben wetenschappers ontdekt dat het beheersen van het niveau van het eiwit GDNF essentieel is voor de juiste overdracht van dopamine, de feel-good neurotransmitter, in de hersenen. GDNF-niveaus dalen drastisch wanneer alcoholisten zich onthouden van drinken, wat leidt tot een tekort aan dopamine en een gevoel van ongemak, waardoor alcoholisten weer naar alcohol grijpen. Gentherapie wordt nu beschouwd als een manier om de GDNF-niveaus te 'repareren', wat een oplossing zou kunnen zijn voor degenen die lijden aan alcoholisme.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"nl",
                key:"updatedAt": string:"2025-02-10T12:52:31.682",
                key:"__typename": string:"ContentItemTranslation"
            },
            {
                key:"title": string:"Tutkijat saattavat olla lähellä mullistavaa parannuskeinoa alkoholismille.",
                key:"uid": string:"8da8d568-a4e9-4783-a64d-494410d8c7ee",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Geeniterapian avulla tutkijat ovat havainneet, että GDNF-proteiinin tason hallinta on avainasemassa dopamiinin, hyvän olon välittäjäaineen, oikeassa siirrossa aivoissa. GDNF-tasot romahtavat, kun alkoholistit pidättäytyvät juomasta, mikä johtaa dopamiinin puutteeseen ja epämukavuuden tunteeseen, mikä saa alkoholistit turvautumaan juomiseen. Geeniterapian ajatellaan nyt 'korjaavan' GDNF-tasot, mikä voisi olla ratkaisu alkoholismista kärsiville.",
                key:"contentCleaned": null:null,
                key:"contentItemUid": string:"eaynwovfmq5sqrcq4g7xd5v43qy",
                key:"createdAt": string:"2025-02-10T13:00:14.579",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vaynwovgknwzqrib2njfxfz4hac",
                key:"subtitle": null:null,
                key:"summary": string:"Gene therapyä käyttäen tutkijat ovat havainneet, että GDNF-proteiinin tason hallinta on avainasemassa dopamiinin, hyvän olon välittäjäaineen, oikeassa siirrossa aivoissa. GDNF-tasot romahtavat, kun alkoholistit pidättäytyvät juomisesta, mikä johtaa dopamiinin puutteeseen ja epämukavuuden tunteeseen, mikä saa alkoholistit turvautumaan juomiseen. Gene therapyä pidetään nyt keinona 'korjata' GDNF-tasot, mikä voisi olla ratkaisu alkoholismista kärsiville.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"fi",
                key:"updatedAt": string:"2025-02-10T13:01:02.296",
                key:"__typename": string:"ContentItemTranslation"
            },
            {
                key:"title": string:"Co je správné: výzkumníci mohou být na pokraji revolučního léku na alkoholismus.",
                key:"uid": string:"9a4d3a04-e8a9-4029-99bd-e7a23a7227e2",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Pomocí genové terapie vědci zjistili, že řízení úrovně proteinu GDNF je klíčové pro správný přenos dopaminu, neurotransmiteru, který způsobuje dobrý pocit, v mozku. Úrovně GDNF klesají, když alkoholici abstinují od pití, což vede k nedostatku dopaminu a pocitu nepohodlí, což nutí alkoholiky k návratu k pití. Genová terapie se nyní považuje za způsob, jak 'opravit' úrovně GDNF, což by mohlo být řešením pro ty, kteří trpí alkoholismem.",
                key:"contentCleaned": null:null,
                key:"contentItemUid": string:"eaynwovfmq5sqrcq4g7xd5v43qy",
                key:"createdAt": string:"2025-02-10T13:36:48.468",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vaynwovgknwzqrib2njfxfz4hac",
                key:"subtitle": null:null,
                key:"summary": string:"Pomocí genové terapie vědci zjistili, že řízení úrovně proteinu GDNF je klíčové pro správný přenos dopaminu, neurotransmiteru, který způsobuje dobrý pocit, v mozku. Úrovně GDNF klesají, když alkoholici přestanou pít, což vede k nedostatku dopaminu a pocitu nepohodlí, což nutí alkoholiky k pití. Genová terapie se nyní považuje za způsob, jak 'opravit' úrovně GDNF, což by mohlo být řešením pro ty, kteří trpí alkoholismem.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"cs",
                key:"updatedAt": string:"2025-02-10T13:37:03.119",
                key:"__typename": string:"ContentItemTranslation"
            },
            {
                key:"title": string:"Forskare kan vara på gränsen till en banbrytande bot för alkoholism.",
                key:"uid": string:"9a9e3ad0-5bc0-4429-8737-f9d159c8060a",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Genom genterapi har forskare upptäckt att hantering av nivån av proteinet GDNF är nyckeln till den korrekta överföringen av dopamin, den må-bra neurotransmittorn, i hjärnan. GDNF-nivåerna sjunker dramatiskt när alkoholister avstår från att dricka, vilket leder till en dopaminbrist och känsla av obehag, vilket får alkoholister att återgå till att dricka. Genterapi anses nu kunna 'fixa' GDNF-nivåerna, vilket skulle kunna vara en lösning för dem som lider av alkoholism.",
                key:"contentCleaned": null:null,
                key:"contentItemUid": string:"eaynwovfmq5sqrcq4g7xd5v43qy",
                key:"createdAt": string:"2025-02-10T12:46:01.054",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vaynwovgknwzqrib2njfxfz4hac",
                key:"subtitle": null:null,
                key:"summary": string:"Genom genterapi har forskare upptäckt att hantering av nivån av proteinet GDNF är nyckeln till den korrekta överföringen av dopamin, den må-bra neurotransmittorn, i hjärnan. GDNF-nivåerna sjunker dramatiskt när alkoholister avstår från att dricka, vilket leder till en dopaminbrist och känsla av obehag, vilket får alkoholister att återgå till att dricka. Genterapi anses nu kunna 'fixa' GDNF-nivåerna, vilket skulle kunna vara en lösning för dem som lider av alkoholism.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"sv",
                key:"updatedAt": string:"2025-02-10T12:46:01.055",
                key:"__typename": string:"ContentItemTranslation"
            },
            {
                key:"title": string:"I ricercatori potrebbero essere sull'orlo di una cura rivoluzionaria per l'alcolismo.",
                key:"uid": string:"cc325b3e-574c-4faf-a45a-60c70bdb9cc9",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Utilizzando la terapia genica, gli scienziati hanno scoperto che gestire il livello della proteina GDNF è fondamentale per la corretta trasmissione della dopamina, il neurotrasmettitore del benessere, nel cervello. I livelli di GDNF crollano quando gli alcolisti si astengono dal bere, portando a una carenza di dopamina e a una sensazione di disagio, che spinge gli alcolisti a ricorrere al bere. Si pensa ora che la terapia genica possa 'correggere' i livelli di GDNF, il che potrebbe essere una soluzione per coloro che soffrono di alcolismo.",
                key:"contentCleaned": null:null,
                key:"contentItemUid": string:"eaynwovfmq5sqrcq4g7xd5v43qy",
                key:"createdAt": string:"2025-02-10T12:37:40.719",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vaynwovgknwzqrib2njfxfz4hac",
                key:"subtitle": null:null,
                key:"summary": string:"Utilizzando la terapia genica, gli scienziati hanno scoperto che gestire il livello della proteina GDNF è fondamentale per la corretta trasmissione della dopamina, il neurotrasmettitore del benessere, nel cervello. I livelli di GDNF crollano quando gli alcolisti si astengono dal bere, portando a una carenza di dopamina e a una sensazione di disagio, che spinge gli alcolisti a ricorrere al bere. Si pensa ora che la terapia genica possa 'correggere' i livelli di GDNF, il che potrebbe essere una soluzione per coloro che soffrono di alcolismo.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"it",
                key:"updatedAt": string:"2025-02-10T12:37:40.721",
                key:"__typename": string:"ContentItemTranslation"
            },
            {
                key:"title": string:"Los investigadores pueden estar al borde de una cura revolucionaria para el alcoholismo.",
                key:"uid": string:"d1abe522-f2d3-4049-bba9-52671f7f0735",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Usando terapia génica, los científicos han descubierto que gestionar el nivel de la proteína GDNF es clave para la correcta transmisión de dopamina, el neurotransmisor que produce bienestar, en el cerebro. Los niveles de GDNF caen en picada cuando los alcohólicos se abstienen de beber, lo que lleva a una escasez de dopamina y a una sensación de malestar, lo que hace que los alcohólicos recurran a beber. Se piensa que la terapia génica ahora 'arregla' los niveles de GDNF, lo que podría ser una solución para aquellos que sufren de alcoholismo.",
                key:"contentCleaned": null:null,
                key:"contentItemUid": string:"eaynwovfmq5sqrcq4g7xd5v43qy",
                key:"createdAt": string:"2025-02-10T12:49:06.304",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vaynwovgknwzqrib2njfxfz4hac",
                key:"subtitle": null:null,
                key:"summary": string:"Utilizando la terapia génica, los científicos han descubierto que gestionar el nivel de la proteína GDNF es clave para la correcta transmisión de dopamina, el neurotransmisor que produce bienestar, en el cerebro. Los niveles de GDNF caen en picada cuando los alcohólicos se abstienen de beber, lo que lleva a una escasez de dopamina y a una sensación de malestar, lo que hace que los alcohólicos recurran a la bebida. Se piensa que la terapia génica ahora 'arregla' los niveles de GDNF, lo que podría ser una solución para aquellos que sufren de alcoholismo.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"es",
                key:"updatedAt": string:"2025-02-10T12:49:06.306",
                key:"__typename": string:"ContentItemTranslation"
            },
            {
                key:"title": string:"Les chercheurs pourraient être sur le point de découvrir un remède révolutionnaire contre l'alcoolisme.",
                key:"uid": string:"dbb827a4-7c92-402f-b11e-266188f62694",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"En utilisant la thérapie génique, les scientifiques ont découvert que la gestion du niveau de la protéine GDNF est essentielle à la bonne transmission de la dopamine, le neurotransmetteur du bien-être, dans le cerveau. Les niveaux de GDNF chutent lorsque les alcooliques s'abstiennent de boire, entraînant une pénurie de dopamine et un sentiment d'inconfort, ce qui pousse les alcooliques à recourir à l'alcool. On pense maintenant que la thérapie génique pourrait 'réparer' les niveaux de GDNF, ce qui pourrait être une solution pour ceux qui souffrent d'alcoolisme.",
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                key:"contentItemUid": string:"eaynwovfmq5sqrcq4g7xd5v43qy",
                key:"createdAt": string:"2025-02-10T12:53:39.729",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vaynwovgknwzqrib2njfxfz4hac",
                key:"subtitle": null:null,
                key:"summary": string:"En utilisant la thérapie génique, les scientifiques ont découvert que la gestion du niveau de la protéine GDNF est essentielle à la bonne transmission de la dopamine, le neurotransmetteur du bien-être, dans le cerveau. Les niveaux de GDNF chutent lorsque les alcooliques s'abstiennent de boire, entraînant une pénurie de dopamine et un sentiment d'inconfort, ce qui pousse les alcooliques à recourir à l'alcool. On pense maintenant que la thérapie génique pourrait 'réparer' les niveaux de GDNF, ce qui pourrait être une solution pour ceux qui souffrent d'alcoolisme.",
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                key:"targetLanguage": string:"fr",
                key:"updatedAt": string:"2025-02-10T12:53:39.729",
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                key:"title": string:"Os pesquisadores podem estar à beira de uma cura inovadora para o alcoolismo.",
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                key:"content": string:"Usando terapia gênica, os cientistas descobriram que gerenciar o nível da proteína GDNF é fundamental para a correta transmissão de dopamina, o neurotransmissor do bem-estar, no cérebro. Os níveis de GDNF despencam quando os alcoólatras se abstêm de beber, levando a uma escassez de dopamina e a uma sensação de desconforto, o que faz com que os alcoólatras recorram ao consumo de álcool. A terapia gênica agora é considerada uma forma de 'corrigir' os níveis de GDNF, o que poderia ser uma solução para aqueles que sofrem de alcoolismo.",
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                key:"subtitle": null:null,
                key:"summary": string:"Usando terapia gênica, os cientistas descobriram que gerenciar o nível da proteína GDNF é fundamental para a transmissão correta da dopamina, o neurotransmissor do bem-estar, no cérebro. Os níveis de GDNF despencam quando os alcoólatras se abstêm de beber, levando a uma escassez de dopamina e a uma sensação de desconforto, o que faz com que os alcoólatras recorram ao consumo de álcool. A terapia gênica agora é considerada uma forma de 'corrigir' os níveis de GDNF, o que poderia ser uma solução para aqueles que sofrem de alcoolismo.",
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            {
                key:"title": string:"Vedci môžu byť na pokraji prelomového lieku na alkoholizmus.",
                key:"uid": string:"dedc39ef-2878-45bb-b883-cccc9f23b52d",
                key:"autoTeaserLong": null:null,
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                key:"content": string:"Pomocou génovej terapie vedci objavili, že riadenie úrovne proteínu GDNF je kľúčové pre správny prenos dopamínu, neurotransmiteru, ktorý spôsobuje dobrú náladu, v mozgu. Úrovne GDNF klesajú, keď alkoholici prestanú piť, čo vedie k nedostatku dopamínu a pocitu nepohodlia, čo núti alkoholikov k pitiu. Génová terapia sa teraz považuje za spôsob, ako 'opraviť' úrovne GDNF, čo by mohlo byť riešením pre tých, ktorí trpia alkoholizmom.",
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                key:"createdAt": string:"2025-02-10T12:33:48.815",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vaynwovgknwzqrib2njfxfz4hac",
                key:"subtitle": null:null,
                key:"summary": string:"Pomocou génovej terapie vedci objavili, že riadenie úrovne proteínu GDNF je kľúčové pre správny prenos dopamínu, neurotransmiteru, ktorý spôsobuje dobrú náladu, v mozgu. Úrovne GDNF klesajú, keď alkoholici prestanú piť, čo vedie k nedostatku dopamínu a pocitu nepohodlia, čo núti alkoholikov k pitiu. Génová terapia sa teraz považuje za spôsob, ako 'opraviť' úrovne GDNF, čo by mohlo byť riešením pre tých, ktorí trpia alkoholizmom.",
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                key:"targetLanguage": string:"sk",
                key:"updatedAt": string:"2025-02-10T12:33:48.816",
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            {
                key:"title": string:"Исследователи могут быть на грани революционного лекарства от алкоголизма.",
                key:"uid": string:"e5b77d4a-9aa7-489a-b002-50f150f06d9c",
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                key:"createdAt": string:"2025-02-12T11:55:34.542",
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                key:"metadata": null:null,
                key:"revisionId": string:"vaynwovgknwzqrib2njfxfz4hac",
                key:"subtitle": null:null,
                key:"summary": null:null,
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"ru",
                key:"updatedAt": null:null,
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            {
                key:"title": string:"Forscher könnten kurz vor einem bahnbrechenden Heilmittel gegen Alkoholismus stehen.",
                key:"uid": string:"f4e975e4-16d8-4872-ba70-70d80f0005c6",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Durch Gentherapie haben Wissenschaftler entdeckt, dass die Regulierung des Proteins GDNF entscheidend für die korrekte Übertragung von Dopamin, dem Wohlfühl-Neurotransmitter, im Gehirn ist. Die GDNF-Spiegel sinken drastisch, wenn Alkoholiker auf das Trinken verzichten, was zu einem Dopaminmangel und einem Gefühl des Unbehagens führt, wodurch Alkoholiker wieder zum Trinken greifen. Es wird nun angenommen, dass die Gentherapie die GDNF-Spiegel 'reparieren' kann, was eine Lösung für diejenigen sein könnte, die unter Alkoholismus leiden.",
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                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vaynwovgknwzqrib2njfxfz4hac",
                key:"subtitle": null:null,
                key:"summary": string:"Durch Gentherapie haben Wissenschaftler entdeckt, dass die Regulierung des Proteins GDNF entscheidend für die korrekte Übertragung von Dopamin, dem Wohlfühl-Neurotransmitter, im Gehirn ist. Die GDNF-Spiegel sinken drastisch, wenn Alkoholiker auf das Trinken verzichten, was zu einem Dopaminmangel und einem Gefühl des Unbehagens führt, wodurch Alkoholiker wieder zum Trinken greifen. Es wird nun angenommen, dass die Gentherapie die GDNF-Spiegel 'reparieren' kann, was eine Lösung für diejenigen sein könnte, die unter Alkoholismus leiden.",
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                key:"updatedAt": string:"2025-02-10T13:37:15.066",
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                key:"title": string:"Οι ερευνητές μπορεί να βρίσκονται στα πρόθυρα μιας επαναστατικής θεραπείας για τον αλκοολισμό.",
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                key:"content": string:"Χρησιμοποιώντας γονιδιακή θεραπεία, οι επιστήμονες έχουν ανακαλύψει ότι η διαχείριση του επιπέδου της πρωτεΐνης GDNF είναι το κλειδί για τη σωστή μετάδοση της ντοπαμίνης, του νευροδιαβιβαστή που προκαλεί ευχάριστα συναισθήματα, στον εγκέφαλο. Τα επίπεδα GDNF πέφτουν κατακόρυφα όταν οι αλκοολικοί απέχουν από το ποτό, οδηγώντας σε έλλειψη ντοπαμίνης και αίσθηση δυσφορίας, γεγονός που αναγκάζει τους αλκοολικούς να καταφύγουν στο ποτό. Η γονιδιακή θεραπεία θεωρείται τώρα ότι 'διορθώνει' τα επίπεδα GDNF, κάτι που θα μπορούσε να είναι μια λύση για όσους υποφέρουν από αλκοολισμό.",
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