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What's right: Nanobots fighting cancer

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Pubdate: 11/29/2024
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Researchers at Sweden’s Karolinska Institutet have developed groundbreaking cancer-fighting nanobots that could transform cancer treatment. These tiny robots are designed to deliver more targeted and less harmful therapies than traditional treatments like chemotherapy. Equipped with a hidden “weapon” of hexagonal peptides, the nanobots remain dormant until they encounter the acidic environment typical of solid tumors. Once activated, they precisely target and destroy cancer cells, leaving healthy cells unharmed, thus reducing the side effects of conventional treatments. The success of these nanobots lies in their ability to detect pH differences between healthy and cancerous tissues. In pre-clinical trials, the nanobots were injected into mice with breast cancer, resulting in a 70% reduction in tumor growth compared to a control group. This promising result sets the stage for further studies on their effectiveness in more advanced cancer models and their potential side effects. Though still in the early stages, the technology represents a major step forward in personalized cancer treatment. Future research aims to improve the targeting of these nanobots by attaching proteins or peptides that can bind to specific cancer cells, making treatment even more precise. Researchers are optimistic that this innovation could pave the way for a new, more effective approach to cancer care.
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                key:"summary": string:"Cercetătorii de la Institutul Karolinska din Suedia au dezvoltat nanoboți revoluționari pentru combaterea cancerului, care ar putea transforma tratamentul cancerului. Acești roboți minusculi sunt concepuți pentru a livra terapii mai țintite și mai puțin dăunătoare decât tratamentele tradiționale, cum ar fi chimioterapia. Echipati cu o „armă” ascunsă de peptide hexagonale, nanoboții rămân inactivi până când întâlnesc mediul acid specific tumorilor solide. Odată activați, aceștia vizează și distrug cu precizie celulele canceroase, lăsând celulele sănătoase neafectate, reducând astfel efectele secundare ale tratamentelor convenționale.\n\nSuccesul acestor nanoboți constă în capacitatea lor de a detecta diferențele de pH între țesuturile sănătoase și cele canceroase. În studiile preclinice, nanoboții au fost injectați în șoareci cu cancer mamar, rezultând o reducere de 70% a creșterii tumorii comparativ cu un grup de control. Acest rezultat promițător pregătește terenul pentru studii suplimentare asupra eficacității lor în modele de cancer mai avansate și a posibilelor efecte secundare.\n\nDeși încă în stadiile incipiente, tehnologia reprezintă un pas major înainte în tratamentul personalizat al cancerului. Cercetările viitoare își propun să îmbunătățească țintirea acestor nanoboți prin atașarea de proteine sau peptide care pot lega celulele canceroase specifice, făcând tratamentul și mai precis. Cercetătorii sunt optimiști că această inovație ar putea deschide calea pentru o nouă abordare mai eficientă în îngrijirea cancerului.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"ro",
                key:"updatedAt": string:"2025-02-10T13:05:26.865",
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            },
            {
                key:"title": string:"Što je ispravno: Nanoboti se bore protiv raka",
                key:"uid": string:"28ce4281-d59c-4751-951c-94666678d189",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Istraživači sa švedskog Karolinska instituta razvili su revolucionarne nanobote za borbu protiv raka koji bi mogli transformirati liječenje raka. Ovi mali roboti dizajnirani su za isporuku ciljanijih i manje štetnih terapija od tradicionalnih tretmana poput kemoterapije. Opremljeni skrivenim \"oružjem\" heksagonalnih peptida, nanoboti ostaju uspavani dok ne naiđu na kiselo okruženje tipično za čvrste tumore. Kada se aktiviraju, precizno ciljaju i uništavaju stanice raka, ostavljajući zdrave stanice netaknute, čime se smanjuju nuspojave konvencionalnih tretmana.\n\nUspjeh ovih nanobota leži u njihovoj sposobnosti da detektiraju pH razlike između zdravih i kancerogenih tkiva. U prekliničkim ispitivanjima, nanoboti su ubrizgani u miševe s rakom dojke, što je rezultiralo smanjenjem rasta tumora za 70% u usporedbi s kontrolnom grupom. Ovaj obećavajući rezultat postavlja temelje za daljnje studije o njihovoj učinkovitosti u naprednijim modelima raka i njihovim potencijalnim nuspojavama.\n\nIako su još uvijek u ranim fazama, tehnologija predstavlja veliki korak naprijed u personaliziranom liječenju raka. Buduća istraživanja imaju za cilj poboljšati ciljanje ovih nanobota pričvršćivanjem proteina ili peptida koji se mogu vezati za specifične stanice raka, čineći liječenje još preciznijim. Istraživači su optimistični da bi ova inovacija mogla otvoriti put za novi, učinkovitiji pristup skrbi o raku.",
                key:"contentCleaned": null:null,
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                key:"createdAt": string:"2025-02-10T12:34:19.927",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vayuftyzbjx3qrq2ji2kk4vp64u",
                key:"subtitle": null:null,
                key:"summary": string:"Istraživači sa švedskog Karolinska instituta razvili su revolucionarne nanobote za borbu protiv raka koji bi mogli transformirati liječenje raka. Ovi mali roboti dizajnirani su za isporuku ciljanijih i manje štetnih terapija od tradicionalnih tretmana poput kemoterapije. Opremljeni skrivenim \"oružjem\" heksagonalnih peptida, nanoboti ostaju uspavani dok ne naiđu na kiselo okruženje tipično za čvrste tumore. Kada se aktiviraju, precizno ciljaju i uništavaju stanice raka, ostavljajući zdrave stanice netaknute, čime se smanjuju nuspojave konvencionalnih tretmana.\n\nUspjeh ovih nanobota leži u njihovoj sposobnosti da detektiraju pH razlike između zdravih i kancerogenih tkiva. U prekliničkim ispitivanjima, nanoboti su ubrizgani u miševe s rakom dojke, što je rezultiralo smanjenjem rasta tumora za 70% u usporedbi s kontrolnom grupom. Ovaj obećavajući rezultat postavlja temelje za daljnje studije o njihovoj učinkovitosti u naprednijim modelima raka i njihovim potencijalnim nuspojavama.\n\nIako su još uvijek u ranim fazama, tehnologija predstavlja veliki korak naprijed u personaliziranom liječenju raka. Buduća istraživanja imaju za cilj poboljšati ciljanje ovih nanobota pričvršćivanjem proteina ili peptida koji se mogu vezati za specifične stanice raka, čineći liječenje još preciznijim. Istraživači su optimistični da bi ova inovacija mogla otvoriti put za novi, učinkovitiji pristup skrbi o raku.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"hr",
                key:"updatedAt": string:"2025-02-10T12:34:19.928",
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            {
                key:"title": string:"Co je správné: Nanoboty bojující proti rakovině",
                key:"uid": string:"39c4ea24-55dd-48ba-815d-bf11d0e14423",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Výzkumníci na švédském Karolinska Institutet vyvinuli revoluční nanoboty bojující proti rakovině, které by mohly transformovat léčbu rakoviny. Tyto malé roboty jsou navrženy tak, aby dodávaly cílenější a méně škodlivé terapie než tradiční léčby, jako je chemoterapie. Vybaveny skrytým „zbraní“ hexagonálních peptidů, nanoboty zůstávají nečinné, dokud se nesetkají s kyselým prostředím typickým pro solidní nádory. Jakmile jsou aktivovány, přesně cílí a ničí rakovinné buňky, přičemž zdravé buňky zůstávají nepoškozené, čímž se snižují vedlejší účinky konvenčních léčeb.\n\nÚspěch těchto nanobotů spočívá v jejich schopnosti detekovat rozdíly pH mezi zdravými a rakovinnými tkáněmi. V preklinických studiích byly nanoboty injikovány do myší s rakovinou prsu, což vedlo k 70% snížení růstu nádoru ve srovnání s kontrolní skupinou. Tento slibný výsledek vytváří základ pro další studie o jejich účinnosti v pokročilejších modelech rakoviny a jejich potenciálních vedlejších účincích.\n\nI když jsou stále v rané fázi, technologie představuje významný krok vpřed v personalizované léčbě rakoviny. Budoucí výzkum si klade za cíl zlepšit cílení těchto nanobotů připojením proteinů nebo peptidů, které se mohou vázat na specifické rakovinné buňky, což činí léčbu ještě přesnější. Výzkumníci jsou optimističtí, že tato inovace by mohla otevřít cestu k novému, účinnějšímu přístupu k péči o rakovinu.",
                key:"contentCleaned": null:null,
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                key:"createdAt": string:"2025-02-10T13:36:40.849",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vayuftyzbjx3qrq2ji2kk4vp64u",
                key:"subtitle": null:null,
                key:"summary": string:"Výzkumníci na švédském Karolinska Institutet vyvinuli revoluční nanoboty bojující proti rakovině, které by mohly transformovat léčbu rakoviny. Tyto malé roboty jsou navrženy tak, aby dodávaly cílenější a méně škodlivé terapie než tradiční léčby, jako je chemoterapie. Vybaveny skrytým „zbraní“ hexagonálních peptidů, nanoboty zůstávají nečinné, dokud se nesetkají s kyselým prostředím typickým pro solidní nádory. Jakmile jsou aktivovány, přesně cílí a ničí rakovinné buňky, přičemž zdravé buňky zůstávají nepoškozené, čímž se snižují vedlejší účinky konvenčních léčeb.\n\nÚspěch těchto nanobotů spočívá v jejich schopnosti detekovat rozdíly pH mezi zdravými a rakovinnými tkáněmi. V preklinických studiích byly nanoboty injikovány do myší s rakovinou prsu, což vedlo k 70% snížení růstu nádoru ve srovnání s kontrolní skupinou. Tento slibný výsledek vytváří základ pro další studie o jejich účinnosti v pokročilejších modelech rakoviny a jejich potenciálních vedlejších účincích.\n\nI když jsou stále v rané fázi, technologie představuje významný krok vpřed v personalizované léčbě rakoviny. Budoucí výzkum si klade za cíl zlepšit cílení těchto nanobotů připojením proteinů nebo peptidů, které se mohou vázat na specifické rakovinné buňky, což činí léčbu ještě přesnější. Výzkumníci jsou optimističtí, že tato inovace by mohla otevřít cestu k novému, účinnějšímu přístupu k péči o rakovinu.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"cs",
                key:"updatedAt": string:"2025-02-10T13:36:55.542",
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            {
                key:"title": string:"Какво е правилно: Наноботи, борещи се с рака",
                key:"uid": string:"551b70a5-052a-413a-a1b4-70eff5e4aeee",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Изследователи от шведския Каролински институт разработиха революционни наноботи за борба с рака, които биха могли да трансформират лечението на рака. Тези малки роботи са проектирани да доставят по-целенасочени и по-малко вредни терапии в сравнение с традиционните лечения като химиотерапия. Оборудвани с скрито \"оръжие\" от хексагонални пептиди, наноботите остават неактивни, докато не срещнат киселинната среда, типична за солидни тумори. След активиране, те точно целят и унищожават раковите клетки, оставяйки здравите клетки непокътнати, като по този начин намаляват страничните ефекти на конвенционалните лечения.\n\nУспехът на тези наноботи се крие в тяхната способност да откриват разлики в pH между здрави и ракови тъкани. В предклинични изпитания, наноботите бяха инжектирани в мишки с рак на гърдата, което доведе до 70% намаление на растежа на тумора в сравнение с контролна група. Този обещаващ резултат поставя основите за по-нататъшни изследвания относно тяхната ефективност в по-напреднали модели на рак и потенциалните им странични ефекти.\n\nВъпреки че все още са в ранните етапи, технологията представлява значителна стъпка напред в персонализираното лечение на рака. Бъдещите изследвания целят да подобрят целенасочването на тези наноботи, като прикрепят протеини или пептиди, които могат да се свързват със специфични ракови клетки, правейки лечението още по-прецизно. Изследователите са оптимисти, че тази иновация може да прокара пътя за нов, по-ефективен подход към лечението на рака.",
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                key:"createdAt": string:"2025-02-10T13:23:13.995",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vayuftyzbjx3qrq2ji2kk4vp64u",
                key:"subtitle": null:null,
                key:"summary": string:"Изследователи от шведския Каролински институт разработиха революционни наноботи за борба с рака, които биха могли да трансформират лечението на рака. Тези малки роботи са проектирани да доставят по-целенасочени и по-малко вредни терапии в сравнение с традиционните лечения като химиотерапия. Оборудвани с скрито \"оръжие\" от хексагонални пептиди, наноботите остават неактивни, докато не срещнат киселинната среда, типична за солидни тумори. След активиране, те точно целят и унищожават раковите клетки, оставяйки здравите клетки непокътнати, като по този начин намаляват страничните ефекти на конвенционалните лечения.\n\nУспехът на тези наноботи се крие в тяхната способност да откриват разлики в pH между здрави и ракови тъкани. В предклинични изпитания, наноботите бяха инжектирани в мишки с рак на гърдата, което доведе до 70% намаление на растежа на тумора в сравнение с контролна група. Този обещаващ резултат поставя основите за допълнителни изследвания относно тяхната ефективност в по-напреднали модели на рак и потенциалните им странични ефекти.\n\nВъпреки че все още са в ранните етапи, технологията представлява значителна стъпка напред в персонализираното лечение на рака. Бъдещите изследвания целят да подобрят целенасочването на тези наноботи, като прикрепят протеини или пептиди, които могат да се свързват със специфични ракови клетки, правейки лечението още по-прецизно. Изследователите са оптимисти, че тази иновация може да прокара пътя за нов, по-ефективен подход към лечението на рака.",
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                key:"targetLanguage": string:"bg",
                key:"updatedAt": string:"2025-02-10T13:23:32.127",
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            {
                key:"title": string:"Nanobotit taistelevat syöpää vastaan",
                key:"uid": string:"670c61ce-4b65-44cf-971c-aa3cb5f66714",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Ruotsin Karoliinisessa instituutissa tutkijat ovat kehittäneet mullistavia syöpää torjuvia nanobotteja, jotka voisivat muuttaa syöpähoitoa. Nämä pienet robotit on suunniteltu toimittamaan kohdennetumpia ja vähemmän haitallisia hoitoja kuin perinteiset hoidot, kuten kemoterapia. Piilotetun \"aseen\" kuusikulmaisten peptidien avulla nanobotit pysyvät lepotilassa, kunnes ne kohtaavat kiinteille kasvaimille tyypillisen happaman ympäristön. Kun ne aktivoituvat, ne kohdistavat tarkasti ja tuhoavat syöpäsoluja, jättäen terveet solut vahingoittumattomiksi, mikä vähentää perinteisten hoitojen sivuvaikutuksia.\n\nNäiden nanobottien menestys perustuu niiden kykyyn havaita pH-erot terveiden ja syöpäisten kudosten välillä. Esiklinikkakokeissa nanobotit ruiskutettiin rintasyöpää sairastaville hiirille, mikä johti 70 %:n vähenemiseen kasvaimen kasvussa verrattuna kontrolliryhmään. Tämä lupaava tulos luo pohjan lisätutkimuksille niiden tehokkuudesta edistyneemmissä syöpämalleissa ja mahdollisista sivuvaikutuksista.\n\nVaikka teknologia on vielä varhaisessa vaiheessa, se edustaa suurta askelta eteenpäin henkilökohtaisessa syöpähoidossa. Tulevaisuuden tutkimuksen tavoitteena on parantaa näiden nanobottien kohdistamista liittämällä proteiineja tai peptidejä, jotka voivat sitoutua tiettyihin syöpäsoluihin, mikä tekee hoidosta entistä tarkempaa. Tutkijat ovat optimistisia, että tämä innovaatio voisi avata tietä uudelle, tehokkaammalle lähestymistavalle syöpätutkimuksessa.",
                key:"contentCleaned": null:null,
                key:"contentItemUid": string:"eayuftyynqn7qrorfo6vq3w6yki",
                key:"createdAt": string:"2025-02-10T13:00:07.344",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vayuftyzbjx3qrq2ji2kk4vp64u",
                key:"subtitle": null:null,
                key:"summary": string:"Ruotsin Karoliinisessa instituutissa tutkijat ovat kehittäneet mullistavia syöpää torjuvia nanobotteja, jotka voisivat muuttaa syöpähoitoa. Nämä pienet robotit on suunniteltu toimittamaan kohdennetumpia ja vähemmän haitallisia hoitoja kuin perinteiset hoidot, kuten kemoterapia. Piilotetun \"aseen\" kuusikulmaisten peptidien avulla nanobotit pysyvät lepotilassa, kunnes ne kohtaavat kiinteille kasvaimille tyypillisen happaman ympäristön. Kun ne aktivoituvat, ne kohdistavat tarkasti ja tuhoavat syöpäsoluja, jättäen terveet solut vahingoittumattomiksi, mikä vähentää perinteisten hoitojen sivuvaikutuksia.\n\nNäiden nanobottien menestys perustuu niiden kykyyn havaita pH-erot terveiden ja syöpäisten kudosten välillä. Esiklinikkakokeissa nanobotit ruiskutettiin rintasyöpää sairastaville hiirille, mikä johti 70 %:n vähenemiseen kasvaimen kasvussa verrattuna kontrolliryhmään. Tämä lupaava tulos luo pohjan lisätutkimuksille niiden tehokkuudesta edistyneemmillä syöpämalleilla ja mahdollisista sivuvaikutuksista.\n\nVaikka teknologia on vielä varhaisessa vaiheessa, se edustaa suurta askelta eteenpäin henkilökohtaisessa syöpähoidossa. Tulevaisuuden tutkimus pyrkii parantamaan näiden nanobottien kohdistamista liittämällä proteiineja tai peptidejä, jotka voivat sitoutua tiettyihin syöpäsoluihin, mikä tekee hoidosta entistä tarkempaa. Tutkijat ovat optimistisia, että tämä innovaatio voisi avata tietä uudelle, tehokkaammalle lähestymistavalle syöpätutkimuksessa.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"fi",
                key:"updatedAt": string:"2025-02-10T13:00:55.801",
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            {
                key:"title": string:"Qu'est-ce qui est juste : des nanobots combattant le cancer",
                key:"uid": string:"671ae550-1c17-46eb-b56c-55d4253b187d",
                key:"autoTeaserLong": null:null,
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                key:"content": string:"Des chercheurs de l'Institut Karolinska en Suède ont développé des nanobots révolutionnaires de lutte contre le cancer qui pourraient transformer le traitement du cancer. Ces minuscules robots sont conçus pour délivrer des thérapies plus ciblées et moins nocives que les traitements traditionnels comme la chimiothérapie. Équipés d'une \"arme\" cachée de peptides hexagonaux, les nanobots restent dormants jusqu'à ce qu'ils rencontrent l'environnement acide typique des tumeurs solides. Une fois activés, ils ciblent et détruisent précisément les cellules cancéreuses, laissant les cellules saines indemnes, réduisant ainsi les effets secondaires des traitements conventionnels.\n\nLe succès de ces nanobots réside dans leur capacité à détecter les différences de pH entre les tissus sains et cancéreux. Lors d'essais précliniques, les nanobots ont été injectés dans des souris atteintes de cancer du sein, entraînant une réduction de 70 % de la croissance tumorale par rapport à un groupe témoin. Ce résultat prometteur ouvre la voie à d'autres études sur leur efficacité dans des modèles de cancer plus avancés et leurs effets secondaires potentiels.\n\nBien qu'encore à ses débuts, la technologie représente un pas en avant majeur dans le traitement personnalisé du cancer. Les recherches futures visent à améliorer le ciblage de ces nanobots en attachant des protéines ou des peptides qui peuvent se lier à des cellules cancéreuses spécifiques, rendant le traitement encore plus précis. Les chercheurs sont optimistes quant à ce que cette innovation pourrait ouvrir la voie à une nouvelle approche, plus efficace, des soins contre le cancer.",
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                key:"createdAt": string:"2025-02-10T12:53:31.453",
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                key:"revisionId": string:"vayuftyzbjx3qrq2ji2kk4vp64u",
                key:"subtitle": null:null,
                key:"summary": string:"Des chercheurs de l'Institut Karolinska en Suède ont développé des nanobots révolutionnaires de lutte contre le cancer qui pourraient transformer le traitement du cancer. Ces minuscules robots sont conçus pour délivrer des thérapies plus ciblées et moins nocives que les traitements traditionnels comme la chimiothérapie. Équipés d'une \"arme\" cachée de peptides hexagonaux, les nanobots restent dormants jusqu'à ce qu'ils rencontrent l'environnement acide typique des tumeurs solides. Une fois activés, ils ciblent et détruisent précisément les cellules cancéreuses, laissant les cellules saines indemnes, réduisant ainsi les effets secondaires des traitements conventionnels.\n\nLe succès de ces nanobots réside dans leur capacité à détecter les différences de pH entre les tissus sains et cancéreux. Lors d'essais précliniques, les nanobots ont été injectés dans des souris atteintes de cancer du sein, entraînant une réduction de 70 % de la croissance tumorale par rapport à un groupe témoin. Ce résultat prometteur ouvre la voie à d'autres études sur leur efficacité dans des modèles de cancer plus avancés et leurs effets secondaires potentiels.\n\nBien qu'encore à ses débuts, la technologie représente un pas en avant majeur dans le traitement personnalisé du cancer. Les recherches futures visent à améliorer le ciblage de ces nanobots en attachant des protéines ou des peptides qui peuvent se lier à des cellules cancéreuses spécifiques, rendant le traitement encore plus précis. Les chercheurs sont optimistes quant à ce que cette innovation pourrait ouvrir la voie à une nouvelle approche, plus efficace, des soins contre le cancer.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"fr",
                key:"updatedAt": string:"2025-02-10T12:53:31.454",
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            {
                key:"title": string:"Vad är rätt: Nanobots som bekämpar cancer",
                key:"uid": string:"67c31bcc-610f-4880-86ae-581b29b47270",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": null:null,
                key:"contentCleaned": null:null,
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                key:"createdAt": string:"2025-02-12T11:54:59.387",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vayuftyzbjx3qrq2ji2kk4vp64u",
                key:"subtitle": null:null,
                key:"summary": null:null,
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"sv",
                key:"updatedAt": null:null,
                key:"__typename": string:"ContentItemTranslation"
            },
            {
                key:"title": string:"Wat is juist: Nanobots die kanker bestrijden",
                key:"uid": string:"719aba8a-5682-4836-948c-dee277885bac",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Onderzoekers van het Karolinska Institutet in Zweden hebben baanbrekende kankerbestrijdende nanobots ontwikkeld die de kankerbehandeling zouden kunnen transformeren. Deze kleine robots zijn ontworpen om gerichter en minder schadelijke therapieën te leveren dan traditionele behandelingen zoals chemotherapie. Uitgerust met een verborgen “wapen” van hexagonale peptiden, blijven de nanobots inactief totdat ze de zure omgeving tegenkomen die typisch is voor solide tumoren. Eenmaal geactiveerd, richten ze zich nauwkeurig op en vernietigen ze kankercellen, terwijl gezonde cellen ongedeerd blijven, waardoor de bijwerkingen van conventionele behandelingen worden verminderd.\n\nHet succes van deze nanobots ligt in hun vermogen om pH-verschillen tussen gezonde en kankertweefsels te detecteren. In preklinische proeven werden de nanobots geïnjecteerd in muizen met borstkanker, wat resulteerde in een vermindering van 70% in tumorgroei vergeleken met een controlegroep. Dit veelbelovende resultaat legt de basis voor verder onderzoek naar hun effectiviteit in meer geavanceerde kankermodellen en hun potentiële bijwerkingen.\n\nHoewel ze zich nog in de vroege stadia bevinden, vertegenwoordigt de technologie een belangrijke stap voorwaarts in gepersonaliseerde kankerbehandeling. Toekomstig onderzoek is gericht op het verbeteren van de targeting van deze nanobots door eiwitten of peptiden toe te voegen die kunnen binden aan specifieke kankercellen, waardoor de behandeling nog preciezer wordt. Onderzoekers zijn optimistisch dat deze innovatie de weg zou kunnen effenen voor een nieuwe, effectievere benadering van kankerzorg.",
                key:"contentCleaned": null:null,
                key:"contentItemUid": string:"eayuftyynqn7qrorfo6vq3w6yki",
                key:"createdAt": string:"2025-02-10T12:52:24.154",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vayuftyzbjx3qrq2ji2kk4vp64u",
                key:"subtitle": null:null,
                key:"summary": string:"Onderzoekers van het Karolinska Institutet in Zweden hebben baanbrekende kankerbestrijdende nanobots ontwikkeld die de kankerbehandeling zouden kunnen transformeren. Deze kleine robots zijn ontworpen om gerichter en minder schadelijke therapieën te leveren dan traditionele behandelingen zoals chemotherapie. Uitgerust met een verborgen “wapen” van hexagonale peptiden, blijven de nanobots inactief totdat ze de zure omgeving tegenkomen die typisch is voor solide tumoren. Eenmaal geactiveerd, richten ze zich nauwkeurig op en vernietigen ze kankercellen, terwijl gezonde cellen ongedeerd blijven, waardoor de bijwerkingen van conventionele behandelingen worden verminderd.\n\nHet succes van deze nanobots ligt in hun vermogen om pH-verschillen tussen gezonde en kankertweefsels te detecteren. In preklinische proeven werden de nanobots geïnjecteerd in muizen met borstkanker, wat resulteerde in een vermindering van 70% in tumorgroei vergeleken met een controlegroep. Dit veelbelovende resultaat legt de basis voor verder onderzoek naar hun effectiviteit in meer geavanceerde kankermodellen en hun potentiële bijwerkingen.\n\nHoewel ze zich nog in de vroege stadia bevinden, vertegenwoordigt de technologie een belangrijke stap voorwaarts in gepersonaliseerde kankerbehandeling. Toekomstig onderzoek is gericht op het verbeteren van de targeting van deze nanobots door eiwitten of peptiden toe te voegen die kunnen binden aan specifieke kankercellen, waardoor de behandeling nog preciezer wordt. Onderzoekers zijn optimistisch dat deze innovatie de weg zou kunnen effenen voor een nieuwe, effectievere benadering van kankerzorg.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"nl",
                key:"updatedAt": string:"2025-02-10T12:52:24.154",
                key:"__typename": string:"ContentItemTranslation"
            },
            {
                key:"title": string:"Τι είναι σωστό: Νανορομπότ που πολεμούν τον καρκίνο",
                key:"uid": string:"7f973855-e2d5-4e70-8a98-342884d18fd6",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Οι ερευνητές στο Καρολίνσκα Ινστιτούτο της Σουηδίας έχουν αναπτύξει επαναστατικά νανορομπότ κατά του καρκίνου που θα μπορούσαν να μεταμορφώσουν τη θεραπεία του καρκίνου. Αυτοί οι μικροσκοπικοί ρομπότ είναι σχεδιασμένοι να παρέχουν πιο στοχευμένες και λιγότερο επιβλαβείς θεραπείες από τις παραδοσιακές θεραπείες όπως η χημειοθεραπεία. Εξοπλισμένα με ένα κρυφό “όπλο” από εξαγωνικά πεπτίδια, τα νανορομπότ παραμένουν ανενεργά μέχρι να συναντήσουν το όξινο περιβάλλον που είναι τυπικό για τους στερεούς όγκους. Μόλις ενεργοποιηθούν, στοχεύουν με ακρίβεια και καταστρέφουν τα καρκινικά κύτταρα, αφήνοντας τα υγιή κύτταρα ανέπαφα, μειώνοντας έτσι τις παρενέργειες των συμβατικών θεραπειών.\n\nΗ επιτυχία αυτών των νανορομπότ έγκειται στην ικανότητά τους να ανιχνεύουν διαφορές pH μεταξύ υγιών και καρκινικών ιστών. Σε προκλινικές δοκιμές, τα νανορομπότ εγχύθηκαν σε ποντίκια με καρκίνο του μαστού, με αποτέλεσμα μια μείωση 70% στην ανάπτυξη του όγκου σε σύγκριση με μια ομάδα ελέγχου. Αυτό το υποσχόμενο αποτέλεσμα θέτει τις βάσεις για περαιτέρω μελέτες σχετικά με την αποτελεσματικότητά τους σε πιο προχωρημένα μοντέλα καρκίνου και τις πιθανές παρενέργειές τους.\n\nΑν και βρίσκονται ακόμη στα πρώτα στάδια, η τεχνολογία αντιπροσωπεύει ένα σημαντικό βήμα προς τα εμπρός στη εξατομικευμένη θεραπεία του καρκίνου. Οι μελλοντικές έρευνες στοχεύουν στη βελτίωση της στόχευσης αυτών των νανορομπότ, συνδέοντας πρωτεΐνες ή πεπτίδια που μπορούν να δεσμευτούν σε συγκεκριμένα καρκινικά κύτταρα, καθιστώντας τη θεραπεία ακόμη πιο ακριβή. Οι ερευνητές είναι αισιόδοξοι ότι αυτή η καινοτομία θα μπορούσε να ανοίξει το δρόμο για μια νέα, πιο αποτελεσματική προσέγγιση στη φροντίδα του καρκίνου.",
                key:"contentCleaned": null:null,
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                key:"createdAt": string:"2025-02-10T13:25:36.647",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vayuftyzbjx3qrq2ji2kk4vp64u",
                key:"subtitle": null:null,
                key:"summary": string:"Οι ερευνητές στο Καρολίνσκα Ινστιτούτο της Σουηδίας έχουν αναπτύξει επαναστατικά νανορομπότ κατά του καρκίνου που θα μπορούσαν να μεταμορφώσουν τη θεραπεία του καρκίνου. Αυτοί οι μικροσκοπικοί ρομπότ είναι σχεδιασμένοι να παρέχουν πιο στοχευμένες και λιγότερο επιβλαβείς θεραπείες από τις παραδοσιακές θεραπείες όπως η χημειοθεραπεία. Εξοπλισμένα με ένα κρυφό “όπλο” από εξαγωνικά πεπτίδια, τα νανορομπότ παραμένουν ανενεργά μέχρι να συναντήσουν το όξινο περιβάλλον που είναι τυπικό για τους στερεούς όγκους. Μόλις ενεργοποιηθούν, στοχεύουν με ακρίβεια και καταστρέφουν τα καρκινικά κύτταρα, αφήνοντας τα υγιή κύτταρα ανέπαφα, μειώνοντας έτσι τις παρενέργειες των συμβατικών θεραπειών.\n\nΗ επιτυχία αυτών των νανορομπότ έγκειται στην ικανότητά τους να ανιχνεύουν διαφορές pH μεταξύ υγιών και καρκινικών ιστών. Σε προκλινικές δοκιμές, τα νανορομπότ εγχύθηκαν σε ποντίκια με καρκίνο του μαστού, με αποτέλεσμα μείωση 70% στην ανάπτυξη του όγκου σε σύγκριση με μια ομάδα ελέγχου. Αυτό το υποσχόμενο αποτέλεσμα θέτει τις βάσεις για περαιτέρω μελέτες σχετικά με την αποτελεσματικότητά τους σε πιο προχωρημένα μοντέλα καρκίνου και τις πιθανές παρενέργειές τους.\n\nΑν και βρίσκονται ακόμη στα πρώτα στάδια, η τεχνολογία αντιπροσωπεύει ένα σημαντικό βήμα προς τα εμπρός στη εξατομικευμένη θεραπεία του καρκίνου. Οι μελλοντικές έρευνες στοχεύουν στη βελτίωση της στόχευσης αυτών των νανορομπότ συνδέοντας πρωτεΐνες ή πεπτίδια που μπορούν να δεσμευτούν σε συγκεκριμένα καρκινικά κύτταρα, καθιστώντας τη θεραπεία ακόμη πιο ακριβή. Οι ερευνητές είναι αισιόδοξοι ότι αυτή η καινοτομία θα μπορούσε να ανοίξει το δρόμο για μια νέα, πιο αποτελεσματική προσέγγιση στη φροντίδα του καρκίνου.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"el",
                key:"updatedAt": string:"2025-02-10T13:26:03.335",
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            {
                key:"title": string:"Lo que es correcto: Nanobots luchando contra el cáncer",
                key:"uid": string:"894f147a-88fc-4330-8576-f3d3fc110ddb",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Los investigadores del Karolinska Institutet de Suecia han desarrollado nanobots revolucionarios para combatir el cáncer que podrían transformar el tratamiento del cáncer. Estos pequeños robots están diseñados para ofrecer terapias más específicas y menos dañinas que los tratamientos tradicionales como la quimioterapia. Equipados con un \"arma\" oculta de péptidos hexagonales, los nanobots permanecen inactivos hasta que encuentran el ambiente ácido típico de los tumores sólidos. Una vez activados, apuntan y destruyen con precisión las células cancerosas, dejando las células sanas ilesas, reduciendo así los efectos secundarios de los tratamientos convencionales.\n\nEl éxito de estos nanobots radica en su capacidad para detectar diferencias de pH entre los tejidos sanos y los cancerosos. En ensayos preclínicos, los nanobots fueron inyectados en ratones con cáncer de mama, resultando en una reducción del 70% en el crecimiento tumoral en comparación con un grupo de control. Este resultado prometedor sienta las bases para estudios adicionales sobre su efectividad en modelos de cáncer más avanzados y sus posibles efectos secundarios.\n\nAunque todavía se encuentra en las primeras etapas, la tecnología representa un gran avance en el tratamiento personalizado del cáncer. La investigación futura tiene como objetivo mejorar la orientación de estos nanobots al adjuntar proteínas o péptidos que puedan unirse a células cancerosas específicas, haciendo que el tratamiento sea aún más preciso. Los investigadores son optimistas de que esta innovación podría allanar el camino para un nuevo enfoque más efectivo en el cuidado del cáncer.",
                key:"contentCleaned": null:null,
                key:"contentItemUid": string:"eayuftyynqn7qrorfo6vq3w6yki",
                key:"createdAt": string:"2025-02-10T13:27:00.231",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vayuftyzbjx3qrq2ji2kk4vp64u",
                key:"subtitle": null:null,
                key:"summary": string:"Los investigadores del Karolinska Institutet de Suecia han desarrollado nanobots revolucionarios para combatir el cáncer que podrían transformar el tratamiento del cáncer. Estos pequeños robots están diseñados para ofrecer terapias más específicas y menos dañinas que los tratamientos tradicionales como la quimioterapia. Equipados con un \"arma\" oculta de péptidos hexagonales, los nanobots permanecen inactivos hasta que encuentran el ambiente ácido típico de los tumores sólidos. Una vez activados, apuntan y destruyen con precisión las células cancerosas, dejando las células sanas ilesas, reduciendo así los efectos secundarios de los tratamientos convencionales.\n\nEl éxito de estos nanobots radica en su capacidad para detectar diferencias de pH entre los tejidos sanos y cancerosos. En ensayos preclínicos, los nanobots fueron inyectados en ratones con cáncer de mama, resultando en una reducción del 70% en el crecimiento tumoral en comparación con un grupo de control. Este resultado prometedor sienta las bases para estudios adicionales sobre su efectividad en modelos de cáncer más avanzados y sus posibles efectos secundarios.\n\nAunque aún se encuentra en las primeras etapas, la tecnología representa un gran avance en el tratamiento personalizado del cáncer. La investigación futura tiene como objetivo mejorar la orientación de estos nanobots al adjuntar proteínas o péptidos que puedan unirse a células cancerosas específicas, haciendo que el tratamiento sea aún más preciso. Los investigadores son optimistas de que esta innovación podría allanar el camino para un nuevo enfoque más efectivo en el cuidado del cáncer.",
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                key:"targetLanguage": string:"es",
                key:"updatedAt": string:"2025-02-10T13:27:00.231",
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            },
            {
                key:"title": string:"Что правильно: Наноботы борются с раком",
                key:"uid": string:"a0b5014b-25ad-4d75-998c-e1bcb65268f8",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": null:null,
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                key:"contentItemUid": string:"eayuftyynqn7qrorfo6vq3w6yki",
                key:"createdAt": string:"2025-02-12T11:55:31.952",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vayuftyzbjx3qrq2ji2kk4vp64u",
                key:"subtitle": null:null,
                key:"summary": null:null,
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"ru",
                key:"updatedAt": null:null,
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            },
            {
                key:"title": string:"Co jest właściwe: Nanoboty walczące z rakiem",
                key:"uid": string:"b28e2d3a-3f1f-43bc-aff6-5444c8d7ae8b",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Badacze z Karolinska Institutet w Szwecji opracowali przełomowe nanoboty do walki z rakiem, które mogą zrewolucjonizować leczenie nowotworów. Te maleńkie roboty zostały zaprojektowane w celu dostarczania bardziej ukierunkowanych i mniej szkodliwych terapii niż tradycyjne metody, takie jak chemioterapia. Wyposażone w ukrytą „broń” w postaci heksagonalnych peptydów, nanoboty pozostają w stanie uśpienia, dopóki nie napotkają kwaśnego środowiska typowego dla guzów stałych. Po aktywacji precyzyjnie celują i niszczą komórki rakowe, pozostawiając zdrowe komórki nietknięte, co zmniejsza skutki uboczne tradycyjnych terapii.\n\nSukces tych nanobotów polega na ich zdolności do wykrywania różnic pH między zdrowymi a nowotworowymi tkankami. W badaniach przedklinicznych nanoboty zostały wstrzyknięte do myszy z rakiem piersi, co skutkowało 70% redukcją wzrostu guza w porównaniu do grupy kontrolnej. Ten obiecujący wynik stwarza podstawy do dalszych badań nad ich skutecznością w bardziej zaawansowanych modelach nowotworowych oraz ich potencjalnymi skutkami ubocznymi.\n\nChociaż technologia jest wciąż na wczesnym etapie, stanowi ona istotny krok naprzód w spersonalizowanym leczeniu nowotworów. Przyszłe badania mają na celu poprawę ukierunkowania tych nanobotów poprzez przyłączanie białek lub peptydów, które mogą wiązać się z konkretnymi komórkami rakowymi, co uczyni leczenie jeszcze bardziej precyzyjnym. Badacze są optymistyczni, że ta innowacja może otworzyć drogę do nowego, skuteczniejszego podejścia do opieki nad chorymi na raka.",
                key:"contentCleaned": null:null,
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                key:"createdAt": string:"2025-02-10T13:08:54.468",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vayuftyzbjx3qrq2ji2kk4vp64u",
                key:"subtitle": null:null,
                key:"summary": string:"Badacze z Karolinska Institutet w Szwecji opracowali przełomowe nanoboty do walki z rakiem, które mogą zrewolucjonizować leczenie nowotworów. Te maleńkie roboty zostały zaprojektowane w celu dostarczania bardziej ukierunkowanych i mniej szkodliwych terapii niż tradycyjne metody, takie jak chemioterapia. Wyposażone w ukrytą „broń” w postaci heksagonalnych peptydów, nanoboty pozostają w stanie uśpienia, dopóki nie napotkają kwaśnego środowiska typowego dla guzów stałych. Po aktywacji precyzyjnie celują i niszczą komórki rakowe, pozostawiając zdrowe komórki nietknięte, co zmniejsza skutki uboczne tradycyjnych terapii.\n\nSukces tych nanobotów polega na ich zdolności do wykrywania różnic pH między zdrowymi a nowotworowymi tkankami. W badaniach przedklinicznych nanoboty zostały wstrzyknięte do myszy z rakiem piersi, co skutkowało 70% redukcją wzrostu guza w porównaniu do grupy kontrolnej. Ten obiecujący wynik stwarza podstawy do dalszych badań nad ich skutecznością w bardziej zaawansowanych modelach nowotworowych oraz ich potencjalnymi skutkami ubocznymi.\n\nChociaż technologia jest wciąż na wczesnym etapie, stanowi ona istotny krok naprzód w spersonalizowanym leczeniu nowotworów. Przyszłe badania mają na celu poprawę ukierunkowania tych nanobotów poprzez przyczepienie białek lub peptydów, które mogą wiązać się z konkretnymi komórkami rakowymi, co uczyni leczenie jeszcze bardziej precyzyjnym. Badacze są optymistyczni, że ta innowacja może otworzyć drogę do nowego, skuteczniejszego podejścia do opieki nad pacjentami z rakiem.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"pl",
                key:"updatedAt": string:"2025-02-10T13:09:12.731",
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            {
                key:"title": string:"Čo je správne: Nanoboty bojujúce proti rakovine",
                key:"uid": string:"b93ced48-ae1d-471a-9eb6-39a97b866063",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Výskumníci na Karolinska Institutet vo Švédsku vyvinuli prelomové nanoboty bojujúce proti rakovine, ktoré by mohli transformovať liečbu rakoviny. Tieto malé roboty sú navrhnuté tak, aby poskytovali cielené a menej škodlivé terapie ako tradičné liečby, ako je chemoterapia. Vybavené skrytým „zbraňou“ hexagonálnych peptidov, nanoboty zostávajú nečinné, kým sa nestretnú s kyslým prostredím typickým pre solidné nádory. Po aktivácii presne cielené a ničia rakovinové bunky, pričom zdravé bunky zostávajú nepoškodené, čím sa znižujú vedľajšie účinky konvenčných liečebných metód.\n\nÚspech týchto nanobotov spočíva v ich schopnosti detekovať rozdiely pH medzi zdravými a rakovinovými tkanivami. V predklinických skúškach boli nanoboty injikované do myší s rakovinou prsníka, čo viedlo k 70% zníženiu rastu nádorov v porovnaní s kontrolnou skupinou. Tento sľubný výsledok vytvára základ pre ďalšie štúdie o ich účinnosti v pokročilejších modeloch rakoviny a ich potenciálnych vedľajších účinkoch.\n\nHoci sú stále v počiatočných fázach, technológia predstavuje významný krok vpred v personalizovanej liečbe rakoviny. Budúci výskum sa zameriava na zlepšenie cielenia týchto nanobotov pripojením proteínov alebo peptidov, ktoré sa môžu viazať na konkrétne rakovinové bunky, čím sa liečba stane ešte presnejšou. Výskumníci sú optimistickí, že táto inovácia by mohla otvoriť cestu pre nový, účinnejší prístup k starostlivosti o rakovinu.",
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                key:"createdAt": string:"2025-02-10T12:40:16.001",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vayuftyzbjx3qrq2ji2kk4vp64u",
                key:"subtitle": null:null,
                key:"summary": string:"Výskumníci na Karolinska Institutet vo Švédsku vyvinuli prelomové nanoboty bojujúce proti rakovine, ktoré by mohli transformovať liečbu rakoviny. Tieto malé roboty sú navrhnuté tak, aby poskytovali cielené a menej škodlivé terapie ako tradičné liečby, ako je chemoterapia. Vybavené skrytým „zbraňou“ hexagonálnych peptidov, nanoboty zostávajú nečinné, kým nenarazia na kyslé prostredie typické pre solidné nádory. Po aktivácii presne cielené a ničia rakovinové bunky, pričom zdravé bunky zostávajú nepoškodené, čím sa znižujú vedľajšie účinky konvenčných liečebných metód.\n\nÚspech týchto nanobotov spočíva v ich schopnosti detekovať rozdiely pH medzi zdravými a rakovinovými tkanivami. V predklinických skúškach boli nanoboty injikované do myší s rakovinou prsníka, čo viedlo k 70% zníženiu rastu nádoru v porovnaní s kontrolnou skupinou. Tento sľubný výsledok vytvára priestor pre ďalšie štúdie o ich účinnosti v pokročilejších modeloch rakoviny a ich potenciálnych vedľajších účinkoch.\n\nAj keď sú stále v počiatočných fázach, technológia predstavuje významný krok vpred v personalizovanej liečbe rakoviny. Budúci výskum sa zameriava na zlepšenie cielenia týchto nanobotov pripojením proteínov alebo peptidov, ktoré sa môžu viazať na konkrétne rakovinové bunky, čím sa liečba stane ešte presnejšou. Výskumníci sú optimistickí, že táto inovácia by mohla otvoriť cestu pre nový, účinnejší prístup k starostlivosti o rakovinu.",
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                key:"targetLanguage": string:"sk",
                key:"updatedAt": string:"2025-02-10T12:40:59.235",
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            {
                key:"title": string:"Mi a helyes: Nanobotok a rák ellen harcolnak",
                key:"uid": string:"cdbf789a-8069-430e-ac92-b1c060106fa5",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"A svéd Karolinska Intézet kutatói áttörő rákellenes nanobotokat fejlesztettek ki, amelyek átalakíthatják a rákkezelést. Ezek a kis robotok célzottabb és kevésbé káros terápiák szállítására lettek tervezve, mint a hagyományos kezelések, például a kemoterápia. A hexagonális peptidek rejtett \"fegyverével\" felszerelt nanobotok inaktívak maradnak, amíg nem találkoznak a szilárd daganatokra jellemző savas környezettel. Miután aktiválódtak, pontosan célozzák meg és pusztítják el a ráksejteket, miközben az egészséges sejteket érintetlenül hagyják, így csökkentve a hagyományos kezelések mellékhatásait.\n\nEzeknek a nanobotoknak a sikere abban rejlik, hogy képesek észlelni a pH-különbségeket az egészséges és a rákos szövetek között. Előklinikai vizsgálatok során a nanobotokat emlőrákos egerekbe injektálták, ami a daganat növekedésének 70%-os csökkenését eredményezte a kontrollcsoporthoz képest. Ez az ígéretes eredmény megalapozza a további kutatásokat a hatékonyságukról fejlettebb rákmodellekben és a potenciális mellékhatásaikról.\n\nBár még a korai szakaszban vannak, a technológia jelentős előrelépést jelent a személyre szabott rákkezelés terén. A jövőbeli kutatások célja, hogy javítsák ezeknek a nanobotoknak a célzását azáltal, hogy olyan fehérjéket vagy peptideket kapcsolnak hozzájuk, amelyek képesek kötődni a specifikus ráksejtekhez, így a kezelés még pontosabbá válik. A kutatók optimisták, hogy ez az innováció új, hatékonyabb megközelítést nyithat meg a rákkezelés terén.",
                key:"contentCleaned": null:null,
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                key:"createdAt": string:"2025-02-10T12:30:41.955",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vayuftyzbjx3qrq2ji2kk4vp64u",
                key:"subtitle": null:null,
                key:"summary": string:"A svéd Karolinska Intézet kutatói áttörő rákellenes nanobotokat fejlesztettek ki, amelyek átalakíthatják a rákkezelést. Ezek a kis robotok célzottabb és kevésbé káros terápiák szállítására lettek tervezve, mint a hagyományos kezelések, például a kemoterápia. A hexagonális peptidek rejtett \"fegyverével\" felszerelt nanobotok inaktív állapotban maradnak, amíg nem találkoznak a szilárd daganatokra jellemző savas környezettel. Miután aktiválódtak, pontosan célozzák meg és pusztítják el a ráksejteket, miközben az egészséges sejteket érintetlenül hagyják, így csökkentve a hagyományos kezelések mellékhatásait.\n\nEzeknek a nanobotoknak a sikere abban rejlik, hogy képesek észlelni a pH-különbségeket az egészséges és a rákos szövetek között. Előklinikai vizsgálatok során a nanobotokat emlőrákos egerekbe injektálták, ami a daganatnövekedés 70%-os csökkenését eredményezte a kontrollcsoporthoz képest. Ez az ígéretes eredmény megalapozza a további kutatásokat a hatékonyságukról fejlettebb rákmodellekben és a potenciális mellékhatásaikról.\n\nBár még a korai szakaszban vannak, a technológia jelentős előrelépést jelent a személyre szabott rákkezelés terén. A jövőbeli kutatások célja, hogy javítsák ezeknek a nanobotoknak a célzását azáltal, hogy olyan fehérjéket vagy peptideket kapcsolnak hozzájuk, amelyek képesek kötődni a specifikus ráksejtekhez, így a kezelés még pontosabbá válik. A kutatók optimisták, hogy ez az innováció új, hatékonyabb megközelítést nyithat a rákkezelésben.",
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                key:"targetLanguage": string:"hu",
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            {
                key:"title": string:"Was ist richtig: Nanobots, die gegen Krebs kämpfen",
                key:"uid": string:"cde09c9c-e6e2-449d-a443-62c319f8daa5",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Forscher am Karolinska Institutet in Schweden haben bahnbrechende krebsbekämpfende Nanobots entwickelt, die die Krebsbehandlung transformieren könnten. Diese winzigen Roboter sind darauf ausgelegt, gezieltere und weniger schädliche Therapien als traditionelle Behandlungen wie Chemotherapie zu liefern. Ausgestattet mit einer versteckten „Waffe“ aus hexagonalen Peptiden, bleiben die Nanobots inaktiv, bis sie auf die saure Umgebung stoßen, die typisch für solide Tumoren ist. Sobald sie aktiviert werden, zielen sie präzise auf Krebszellen ab und zerstören diese, während gesunde Zellen unversehrt bleiben, wodurch die Nebenwirkungen herkömmlicher Behandlungen reduziert werden.\n\nDer Erfolg dieser Nanobots liegt in ihrer Fähigkeit, pH-Unterschiede zwischen gesunden und krebskranken Geweben zu erkennen. In präklinischen Studien wurden die Nanobots in Mäuse mit Brustkrebs injiziert, was zu einer 70%igen Reduktion des Tumorwachstums im Vergleich zu einer Kontrollgruppe führte. Dieses vielversprechende Ergebnis ebnet den Weg für weitere Studien zu ihrer Wirksamkeit in fortgeschritteneren Krebsmodellen und ihren potenziellen Nebenwirkungen.\n\nObwohl sich die Technologie noch in einem frühen Stadium befindet, stellt sie einen großen Fortschritt in der personalisierten Krebsbehandlung dar. Zukünftige Forschungen zielen darauf ab, die Zielgenauigkeit dieser Nanobots zu verbessern, indem Proteine oder Peptide angebracht werden, die an spezifische Krebszellen binden können, was die Behandlung noch präziser macht. Forscher sind optimistisch, dass diese Innovation den Weg für einen neuen, effektiveren Ansatz in der Krebsversorgung ebnen könnte.",
                key:"contentCleaned": null:null,
                key:"contentItemUid": string:"eayuftyynqn7qrorfo6vq3w6yki",
                key:"createdAt": string:"2025-02-10T12:31:53.361",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vayuftyzbjx3qrq2ji2kk4vp64u",
                key:"subtitle": null:null,
                key:"summary": string:"Forscher am Karolinska Institutet in Schweden haben bahnbrechende krebsbekämpfende Nanobots entwickelt, die die Krebsbehandlung revolutionieren könnten. Diese winzigen Roboter sind darauf ausgelegt, gezieltere und weniger schädliche Therapien als herkömmliche Behandlungen wie Chemotherapie zu liefern. Ausgestattet mit einer versteckten „Waffe“ aus hexagonalen Peptiden, bleiben die Nanobots inaktiv, bis sie auf die saure Umgebung stoßen, die typisch für solide Tumoren ist. Sobald sie aktiviert werden, zielen sie präzise auf Krebszellen ab und zerstören diese, während gesunde Zellen unversehrt bleiben, wodurch die Nebenwirkungen herkömmlicher Behandlungen verringert werden.\n\nDer Erfolg dieser Nanobots liegt in ihrer Fähigkeit, pH-Unterschiede zwischen gesunden und krebskranken Geweben zu erkennen. In präklinischen Studien wurden die Nanobots in Mäuse mit Brustkrebs injiziert, was zu einer 70%igen Reduktion des Tumorwachstums im Vergleich zu einer Kontrollgruppe führte. Dieses vielversprechende Ergebnis ebnet den Weg für weitere Studien zu ihrer Wirksamkeit in fortgeschritteneren Krebsmodellen und ihren potenziellen Nebenwirkungen.\n\nObwohl sich die Technologie noch in einem frühen Stadium befindet, stellt sie einen großen Fortschritt in der personalisierten Krebsbehandlung dar. Zukünftige Forschungen zielen darauf ab, die Zielgenauigkeit dieser Nanobots zu verbessern, indem Proteine oder Peptide angebracht werden, die an spezifische Krebszellen binden können, um die Behandlung noch präziser zu gestalten. Forscher sind optimistisch, dass diese Innovation den Weg für einen neuen, effektiveren Ansatz in der Krebsversorgung ebnen könnte.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"de",
                key:"updatedAt": string:"2025-02-10T12:31:53.362",
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            {
                key:"title": string:"O que é certo: Nanobots lutando contra o câncer",
                key:"uid": string:"d0045c82-2cf7-4c40-bdf9-487e6fa5098a",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Pesquisadores do Karolinska Institutet da Suécia desenvolveram nanobots revolucionários para combater o câncer que podem transformar o tratamento do câncer. Esses pequenos robôs são projetados para fornecer terapias mais direcionadas e menos prejudiciais do que os tratamentos tradicionais, como a quimioterapia. Equipados com uma \"arma\" oculta de peptídeos hexagonais, os nanobots permanecem dormentes até encontrarem o ambiente ácido típico dos tumores sólidos. Uma vez ativados, eles visam e destroem precisamente as células cancerosas, deixando as células saudáveis ilesas, reduzindo assim os efeitos colaterais dos tratamentos convencionais.\n\nO sucesso desses nanobots reside em sua capacidade de detectar diferenças de pH entre tecidos saudáveis e cancerosos. Em ensaios pré-clínicos, os nanobots foram injetados em camundongos com câncer de mama, resultando em uma redução de 70% no crescimento tumoral em comparação a um grupo controle. Este resultado promissor prepara o terreno para novos estudos sobre sua eficácia em modelos de câncer mais avançados e seus potenciais efeitos colaterais.\n\nEmbora ainda esteja nos estágios iniciais, a tecnologia representa um grande avanço no tratamento personalizado do câncer. Pesquisas futuras visam melhorar a capacidade de direcionamento desses nanobots, anexando proteínas ou peptídeos que possam se ligar a células cancerosas específicas, tornando o tratamento ainda mais preciso. Os pesquisadores estão otimistas de que essa inovação possa abrir caminho para uma nova abordagem mais eficaz no cuidado do câncer.",
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                key:"createdAt": string:"2025-02-10T13:17:35.694",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
                key:"revisionId": string:"vayuftyzbjx3qrq2ji2kk4vp64u",
                key:"subtitle": null:null,
                key:"summary": string:"Pesquisadores do Karolinska Institutet, na Suécia, desenvolveram nanobots revolucionários para combater o câncer que podem transformar o tratamento do câncer. Esses pequenos robôs são projetados para fornecer terapias mais direcionadas e menos prejudiciais do que os tratamentos tradicionais, como a quimioterapia. Equipados com uma \"arma\" oculta de peptídeos hexagonais, os nanobots permanecem dormentes até encontrarem o ambiente ácido típico dos tumores sólidos. Uma vez ativados, eles visam e destroem precisamente as células cancerígenas, deixando as células saudáveis ilesas, reduzindo assim os efeitos colaterais dos tratamentos convencionais.\n\nO sucesso desses nanobots reside em sua capacidade de detectar diferenças de pH entre tecidos saudáveis e cancerígenos. Em ensaios pré-clínicos, os nanobots foram injetados em camundongos com câncer de mama, resultando em uma redução de 70% no crescimento tumoral em comparação a um grupo controle. Este resultado promissor prepara o terreno para novos estudos sobre sua eficácia em modelos de câncer mais avançados e seus potenciais efeitos colaterais.\n\nEmbora ainda esteja nos estágios iniciais, a tecnologia representa um grande avanço no tratamento personalizado do câncer. Pesquisas futuras visam melhorar a capacidade de direcionamento desses nanobots, anexando proteínas ou peptídeos que possam se ligar a células cancerígenas específicas, tornando o tratamento ainda mais preciso. Os pesquisadores estão otimistas de que essa inovação possa abrir caminho para uma nova abordagem mais eficaz no cuidado do câncer.",
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                key:"targetLanguage": string:"pt",
                key:"updatedAt": string:"2025-02-10T13:17:35.695",
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            {
                key:"title": string:"What's right: Nanobots fighting cancer",
                key:"uid": string:"d9b9cceb-24fb-4337-a915-da6e8a0c6871",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"Researchers at Sweden’s Karolinska Institutet have developed groundbreaking cancer-fighting nanobots that could transform cancer treatment. These tiny robots are designed to deliver more targeted and less harmful therapies than traditional treatments like chemotherapy. Equipped with a hidden “weapon” of hexagonal peptides, the nanobots remain dormant until they encounter the acidic environment typical of solid tumors. Once activated, they precisely target and destroy cancer cells, leaving healthy cells unharmed, thus reducing the side effects of conventional treatments.\n\nThe success of these nanobots lies in their ability to detect pH differences between healthy and cancerous tissues. In pre-clinical trials, the nanobots were injected into mice with breast cancer, resulting in a 70% reduction in tumor growth compared to a control group. This promising result sets the stage for further studies on their effectiveness in more advanced cancer models and their potential side effects.\n\nThough still in the early stages, the technology represents a major step forward in personalized cancer treatment. Future research aims to improve the targeting of these nanobots by attaching proteins or peptides that can bind to specific cancer cells, making treatment even more precise. Researchers are optimistic that this innovation could pave the way for a new, more effective approach to cancer care.",
                key:"contentCleaned": null:null,
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                key:"createdAt": string:"2025-01-24T10:47:16.55",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
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                key:"subtitle": null:null,
                key:"summary": string:"Researchers at Sweden’s Karolinska Institutet have developed groundbreaking cancer-fighting nanobots that could transform cancer treatment. These tiny robots are designed to deliver more targeted and less harmful therapies than traditional treatments like chemotherapy. Equipped with a hidden “weapon” of hexagonal peptides, the nanobots remain dormant until they encounter the acidic environment typical of solid tumors. Once activated, they precisely target and destroy cancer cells, leaving healthy cells unharmed, thus reducing the side effects of conventional treatments.\n\nThe success of these nanobots lies in their ability to detect pH differences between healthy and cancerous tissues. In pre-clinical trials, the nanobots were injected into mice with breast cancer, resulting in a 70% reduction in tumor growth compared to a control group. This promising result sets the stage for further studies on their effectiveness in more advanced cancer models and their potential side effects.\n\nThough still in the early stages, the technology represents a major step forward in personalized cancer treatment. Future research aims to improve the targeting of these nanobots by attaching proteins or peptides that can bind to specific cancer cells, making treatment even more precise. Researchers are optimistic that this innovation could pave the way for a new, more effective approach to cancer care.",
                key:"summaryCleaned": null:null,
                key:"targetLanguage": string:"en",
                key:"updatedAt": string:"2025-02-10T12:59:49.986",
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            },
            {
                key:"title": string:"Nanobotların kanserle savaşıyor olması doğru.",
                key:"uid": string:"da96f60e-c5db-4df9-98cd-4fffaa897cee",
                key:"autoTeaserLong": null:null,
                key:"autoTeaserShort": null:null,
                key:"content": string:"İsveç'teki Karolinska Enstitüsü'nden araştırmacılar, kanser tedavisini dönüştürebilecek çığır açıcı kanserle savaşan nanobotlar geliştirdi. Bu küçük robotlar, kemoterapi gibi geleneksel tedavilere göre daha hedeflenmiş ve daha az zararlı terapiler sunmak üzere tasarlandı. Altıgen peptitlerden oluşan gizli bir \"silah\" ile donatılan nanobotlar, katı tümörlerin tipik asidik ortamıyla karşılaşana kadar uyku halinde kalıyor. Aktive olduklarında, kanser hücrelerini hassas bir şekilde hedef alıp yok ediyorlar, sağlıklı hücrelere zarar vermeden, böylece geleneksel tedavilerin yan etkilerini azaltıyorlar.\n\nBu nanobotların başarısı, sağlıklı ve kanserli dokular arasındaki pH farklarını tespit etme yeteneklerinde yatıyor. Ön klinik denemelerde, nanobotlar meme kanseri olan farelere enjekte edildi ve kontrol grubuna kıyasla tümör büyümesinde %70'lik bir azalma sağlandı. Bu umut verici sonuç, daha ileri kanser modellerindeki etkinlikleri ve potansiyel yan etkileri üzerine daha fazla çalışma için zemin hazırlıyor.\n\nHenüz erken aşamalarda olmasına rağmen, bu teknoloji kişiselleştirilmiş kanser tedavisinde önemli bir ilerlemeyi temsil ediyor. Gelecek araştırmalar, bu nanobotların belirli kanser hücrelerine bağlanabilen proteinler veya peptitler ekleyerek hedeflemelerini geliştirmeyi amaçlıyor, böylece tedavi daha da hassas hale geliyor. Araştırmacılar, bu yeniliğin kanser bakımında yeni ve daha etkili bir yaklaşımın yolunu açabileceğinden umutlu.",
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                key:"createdAt": string:"2025-02-10T13:38:05.422",
                key:"engine": string:"gpt-4o-mini-2024-07-18",
                key:"metadata": null:null,
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                key:"subtitle": null:null,
                key:"summary": string:"İsveç'teki Karolinska Enstitüsü'nden araştırmacılar, kanser tedavisini dönüştürebilecek çığır açıcı kanserle savaşan nanobotlar geliştirdi. Bu küçük robotlar, kemoterapi gibi geleneksel tedavilere göre daha hedeflenmiş ve daha az zararlı terapiler sunmak üzere tasarlandı. Altıgen peptitlerden oluşan gizli bir \"silah\" ile donatılan nanobotlar, katı tümörlerin tipik asidik ortamıyla karşılaşana kadar uyku halinde kalıyor. Aktive olduklarında, kanser hücrelerini hassas bir şekilde hedef alıp yok ediyorlar, sağlıklı hücrelere zarar vermeden, böylece geleneksel tedavilerin yan etkilerini azaltıyorlar.\n\nBu nanobotların başarısı, sağlıklı ve kanserli dokular arasındaki pH farklarını tespit etme yeteneklerinde yatıyor. Ön klinik denemelerde, nanobotlar meme kanseri olan farelere enjekte edildi ve kontrol grubuna kıyasla tümör büyümesinde %70'lik bir azalma sağlandı. Bu umut verici sonuç, daha ileri kanser modellerindeki etkinlikleri ve potansiyel yan etkileri üzerine daha fazla çalışma için zemin hazırlıyor.\n\nHenüz erken aşamalarda olmasına rağmen, bu teknoloji kişiselleştirilmiş kanser tedavisinde önemli bir ilerlemeyi temsil ediyor. Gelecek araştırmalar, bu nanobotların belirli kanser hücrelerine bağlanabilen proteinler veya peptitler ekleyerek hedeflemelerini geliştirmeyi amaçlıyor, böylece tedavi daha da hassas hale geliyor. Araştırmacılar, bu yeniliğin kanser bakımında yeni ve daha etkili bir yaklaşımın yolunu açabileceğinden umutlu.",
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                key:"title": string:"Cosa c'è di giusto: Nanobot che combattono il cancro",
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                key:"content": string:"I ricercatori del Karolinska Institutet in Svezia hanno sviluppato nanobot innovativi per combattere il cancro che potrebbero trasformare il trattamento del cancro. Questi piccoli robot sono progettati per fornire terapie più mirate e meno dannose rispetto ai trattamenti tradizionali come la chemioterapia. Dotati di un “arma” nascosta di peptidi esagonali, i nanobot rimangono inattivi fino a quando non incontrano l'ambiente acido tipico dei tumori solidi. Una volta attivati, mirano e distruggono con precisione le cellule tumorali, lasciando intatte le cellule sane, riducendo così gli effetti collaterali dei trattamenti convenzionali.\n\nIl successo di questi nanobot risiede nella loro capacità di rilevare differenze di pH tra tessuti sani e cancerosi. Negli studi preclinici, i nanobot sono stati iniettati in topi con cancro al seno, portando a una riduzione del 70% della crescita tumorale rispetto a un gruppo di controllo. Questo risultato promettente prepara il terreno per ulteriori studi sulla loro efficacia in modelli di cancro più avanzati e sui loro potenziali effetti collaterali.\n\nAnche se siamo ancora nelle fasi iniziali, la tecnologia rappresenta un passo avanti significativo nel trattamento personalizzato del cancro. La ricerca futura mira a migliorare il targeting di questi nanobot attaccando proteine o peptidi che possono legarsi a cellule tumorali specifiche, rendendo il trattamento ancora più preciso. I ricercatori sono ottimisti che questa innovazione possa aprire la strada a un nuovo approccio più efficace alla cura del cancro.",
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                key:"summary": string:"I ricercatori del Karolinska Institutet in Svezia hanno sviluppato nanobot innovativi per combattere il cancro che potrebbero trasformare il trattamento del cancro. Questi piccoli robot sono progettati per fornire terapie più mirate e meno dannose rispetto ai trattamenti tradizionali come la chemioterapia. Dotati di un “arma” nascosta di peptidi esagonali, i nanobot rimangono inattivi fino a quando non incontrano l'ambiente acido tipico dei tumori solidi. Una volta attivati, mirano e distruggono con precisione le cellule tumorali, lasciando intatte le cellule sane, riducendo così gli effetti collaterali dei trattamenti convenzionali.\n\nIl successo di questi nanobot risiede nella loro capacità di rilevare differenze di pH tra tessuti sani e cancerosi. Negli studi preclinici, i nanobot sono stati iniettati in topi con cancro al seno, portando a una riduzione del 70% della crescita tumorale rispetto a un gruppo di controllo. Questo risultato promettente prepara il terreno per ulteriori studi sulla loro efficacia in modelli di cancro più avanzati e sui loro potenziali effetti collaterali.\n\nAnche se siamo ancora nelle fasi iniziali, la tecnologia rappresenta un passo avanti significativo nel trattamento personalizzato del cancro. La ricerca futura mira a migliorare il targeting di questi nanobot attaccando proteine o peptidi che possono legarsi a cellule tumorali specifiche, rendendo il trattamento ancora più preciso. I ricercatori sono ottimisti che questa innovazione possa aprire la strada a un nuovo approccio più efficace alla cura del cancro.",
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                key:"title": string:"Що правильно: Наноботи борються з раком",
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                key:"title": string:"Šta je ispravno: Nanoboti se bore protiv raka",
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